Dr. Nuno Almeida, PhD

Principal Research Scientist

Amarante, PT.

About

Principal Research Scientist with expertise in oncology, 3D in vitro models, and microphysiological systems. Holds a BSc and MSc in Biochemistry from the University of Coimbra and a PhD in Life Sciences from the University of Strasbourg. Experienced in developing patient‑derived spheroid models for drug screening and contributing to microtissue-based drug discovery technologies.

Work

Hooke Bio Ltd.

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Principal Research Scientist

Shannon, Clare, Ireland

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Summary

Leading research efforts in the development and application of microphysiological 3D microtissue systems for translational drug discovery and screening.

Highlights

Spearheading research program leveraging Mera system for screening of patient‑derived spheroids.

Co-authored recent publication: “Arrhythmia Drug Responses in Cardiac Spheroids: Insights from the Mera Microphysiological System.”

Hooke Bio Ltd.

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Senior Research Scientist

Shannon, Clare, Ireland

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Summary

Developed cancer-related in vitro 3D spheroid models for drug screening applications, focusing on liver cancer (HCC) patient‑derived spheroid systems to model tumor microenvironment and therapeutic responses.

Highlights

Completed PhD‑related research on patient‑derived HCC spheroids used in screening anti‑cancer treatments.

Built expertise in oncology and in vitro 3D models for translational research.

INSERM Institute for Translational Medicine and Liver Disease, University of Strasbourg

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PhD Student

Strasbourg, Grand Est, France

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Summary

Doctoral research focused on development of patient‑derived liver cancer multicellular spheroid models for drug screening and personalized medicine.

Highlights

Designed and validated HCC patient‑derived spheroid model recapitulating tumor microenvironment heterogeneity for functional drug response studies.

University of Vienna

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STSM Grant (Nutredox COST Action CA16112)

Vienna, Wien, Austria

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Summary

Short‑term scientific mission under Nutredox COST Action involving research exchange or collaboration in metabolic/oxidative stress areas.

Universidade Lusófona - CBIOS, Lisbon

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Research Fellow

Lisbon, Lisbon, Portugal

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Summary

Research fellow within Pharmacology and Therapeutics group at CBIOS, developing cellular models as part of academic research.

Universidade Lusófona - Centro Universitário Lisboa

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Monitor

Lisbon, Lisbon, Portugal

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Summary

Academic monitor, assisting teaching or laboratory sessions.

Portugal Telecom

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Telemarketing Assistant

Lisbon, Lisbon, Portugal

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Summary

Short‑term role in telemarketing within telecommunications sector.

ICBR – Coimbra Institute for Clinical and Biomedical Research

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MSc Student

Coimbra, Coimbra, Portugal

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Summary

Master’s research in biochemistry conducted within ICBR.

IPO de Coimbra

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Summer Internship

Coimbra, Coimbra, Portugal

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Summary

Hospital‑based summer internship focused on basic biomedical research.

ICBR – Coimbra Institute for Clinical and Biomedical Research

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Bachelor Internship

Coimbra, Coimbra, Portugal

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Summary

Undergraduate internship in clinical and biomedical research setting.

Education

University of Strasbourg

Strasbourg, Grand Est, France
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PhD Life Sciences

University of Coimbra, Faculty of Sciences and Technology (FCTUC)

Coimbra, Coimbra, Portugal
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MSc Biochemistry

University of Coimbra, Faculty of Sciences and Technology (FCTUC)

Coimbra, Coimbra, Portugal
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BSc Biochemistry

Skills

3D cell culture / patient‑derived spheroid models

3D in vitro models, microphysiological systems, oncobiology.

Oncology research

HCC, liver cancer, drug screening.

Molecular & cellular biology techniques

PCR, Western blot, cell culture.

Biotechnology research

biologia molecular, biologia celular, microbiologia.

Lab software & tools

Microsoft Office.